In order to build a synthetic cell, it is crucial to know how to access the genetic information carried in large DNA molecules. In this work, we used rational analysis and an active learning tool to explore a broad parameter space and to adapt in vitro gene expression to E. coli’s chromosomes, discovering that these […]
New review article has just been published in ACS Chemical Reviews! 🎈🎊 Here we explore exciting research involving enzymatic reaction networks, where we discuss the progress to date and the challenges ahead. You can read it here. Congratulations to all authors: Souvik Ghosh, Mathieu Baltussen, Nikita Ivanov, Rianne Haije, Miglė Jakštaitė, Tao Zhou and Wilhelm […]
Cells live in constantly changing environments. To truly understand how cells process information in their complex natural environment, it is essential to recreate such dynamic environments in the lab and study cell responses. In our work, we have studied how B-cells respond to dynamic environments by creating gradients of increasing hydrogen peroxide levels over time. […]
Congratulations to Bob, Tao and co-authors, who designed training data to control enzymatic reaction networks in flow! The newest article entitled “Iterative design of training data to control intricate enzymatic reaction networks” is now out in Nature Communications! Well done!! 😎🎊🥳 You can read the paper here
On 22 January, 2024, Bob van Sluijs successfully defended his PhD thesis entitled “Decoding Complexity: Maximizing the Information About Partially Observed Nonlinear Networks”. Bob became #26 Dr. in the Huck group! Congratulations Dr. Bob! It’s a well deserved title and you did an amazing job! All the best to your future career! 😎🥳
Right before Christmas break we had an Organic Chemistry Cluster party! This year the topic was bioluminescence! We had a lot of fun and made a POC photo!
It’s that time of the year again! In POC department we have an annual tradition to exchange little Sinterklaas/Christmas presents 🎅🎁. To make the choice easier, we are always gifting socks 🧦 and write a personal poem 📝. We had a lot of fun and enjoyed the time together before the winter holiday!
On 30 November 2023, the 4th General Assembly hybrid meeting of the CORENET consortium took place at the CIAL institute in Madrid, Spain, hosted by partners from the Autonomous University of Madrid (UAM) and National Research Council of Spain (CSIC). During the meeting all partners presented their research updates, after which fruitful discussions gave new […]
On Monday (4 December, 2023) Andrei Sakai successfully defended his PhD thesis entitled “Construction of a minimal synthetic cell”. Andrei became #25 Dr. in the Huck group! Congratulations Dr. Andrei! We’re very proud of you! All the best to your future career! 😎🥳
Last Friday, December 1, the last FMS Annual Meeting 2023 took place in Zwolle, the Netherlands. During this one-day meeting various scientists from FMS Research Center shared the latest updates on their research. Rianne Haije, a PhD student from our group, gave a presentation entitled “Neuromorphic Sensing with a Retrainable Enzymatic Reaction Network” on which […]